![]() ![]() Click image to enlarge.ĪMD stages in the Beckman Scale rely on the size of the drusen. The infrared reflectance image (left) also demonstrates the reticular pattern consistent with RPD. A patient with both a typical drusen phenotype presenting on OCT as sub-RPE drusen deposits and RPD that present as hyperreflective deposits sitting on top of the RPE (right image). Patients who have drusen with homogenous, uniform, moderate internal reflectivity have less risk to develop advanced-stage AMD than those with drusen that are internally hyperreflective, hyporeflective or those with non-uniform internal composition ( Figure 3). The internal structure of drusen as seen on OCT can also give clues to the severity of disease. OCT segmentation allows for various manipulation of images and algorithms for measurable analytics. 3 RPD may also be identified by their reticular pattern on imaging such as infrared reflectance or fundus autofluorescence (FAF) ( Figure 2). RPD present as hyperreflective deposits on OCT that sit above the retinal pigment epithelium (RPE), as opposed to typical drusen deposits, which are sub-RPE. 2,3 In addition, patients with RPD tend to have worse visual function. Reticular pseudodrusen (RPD), also called subretinal drusenoid deposits, are a drusen phenotype associated with higher risk of conversion to advanced-stage AMD, particularly development of geographic atrophy (GA). While most clinicians are aware to look for the presence of drusen on OCT cross-section scans, a variety of additional biomarkers of disease severity can be spotted in regard to atrophic or nonexudative AMD. Age-related Macular Degeneration (AMD)Ī wealth of data can be uncovered when evaluating the OCT cross-section in a patient with confirmed or suspected AMD to better stage the disease and consider the patient’s risk of progression. Keep in mind that this list only scratches the surface of the abundance of information the technology can offer. Here, we’ll discuss how to spot and analyze OCT findings associated with a wide range of retinal pathologies. 1 Using this advanced technology, we can diagnose posterior segment disease earlier and more accurately, identify biomarkers that indicate severity of disease and deepen our understanding of the pathological processes that affect the retina. A strength of OCT is its ability to segment various retina layers, which enables cross-sectional structural examination of the retina along with evaluation of various analytic data such as thickness maps extracted from OCT scans ( Figure 1 ). Its widespread use can be attributed to its ability to deliver a vast amount of high-resolution information regarding the structure of the retina both quickly and safely. I maging with optical coherence tomography (OCT) has become standard in retina care. Six Questions About the Role of OCT in Neuro Evaluations.Check out the other articles featured in this OCT-themed issue: ![]()
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